After this period, despite sharp decreases in air travel, we estimated multiple exportations from large urban centers that coincided with a 25% increase in average traveled distances in national flights. During the early epidemic phase, we found that SARS-CoV-2 spread mostly locally and within state borders. We estimate that most (76%) of the Brazilian strains fell in three clades that were introduced from Europe between 22 February and 11 March 2020. Sequencing of 427 new genomes and analysis of a geographically representative genomic dataset identified >100 international virus introductions in Brazil. Using a mobility-driven transmission model, we show that NPIs reduced the reproduction number from >3 to 1 to 1.6 in São Paulo and Rio de Janeiro. Because of limited available data, assessments of the impact of nonpharmaceutical interventions (NPIs) on this virus spread remain challenging. Sabino, and Nuno Rodrigues Faria +76 authors +74 authors +69 authors fewer Authors Info & Affiliationsīrazil currently has one of the fastest-growing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemics in the world. Vasconcelos, Samir Bhatt, Philippe Lemey, Chieh-Hsi Wu, Andrew Rambaut, Nick J. Costa, José Luiz Proenca-Modena, Ana Tereza R. Nogueira, Brazil-UK Centre for Arbovirus Discovery, Diagnosis, Genomics and Epidemiology (CADDE) Genomic Network, Neil M. Hill, Andreza Aruska de Souza Santos, Camila L. Garcia, Maria Luiza Moretti, Mauricio W. Lima, José Eduardo Levi, Celso Granato, Giulia M. Manuli, Julien Thézé, Luiz Almeida, Mariane T.
0 Comments
Leave a Reply. |